Molecular docking study of jak1 selective inhibitors
for inflammatory bowel disease

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: CHOI, Sun (Ewha Womans University, Korea, Republic Of)
  • Co-author(s): Sun Choi
    Jongmi Park
    Minghua Cui
    Soogung Kang
  • Abstract:

    Background

    Janus kinase (JAK) is one of receptor-associated tyrosine kinases and consists of 4 subtypes: JAK1, JAK2, JAK3, and TYK2. JAKs play a critical role in the regulation of cytokine receptor signaling and signal transducer and activators of transcription (STAT) signaling cascade in mucosal immune cells. The abnormal cell proliferation leads..

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