Adolescent, but not adult, rats exposed to cigarette smoke showed enhanced response to the addictive effects of nicotine during adulthood

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: CHEONG, Jae Hoon (Uimyung Research Instititue for Neuroscience/Sahmyook University, School of Pharmacy, Seoul, Korea, Republic Of)
  • Co-author(s): June Bryan de la Peña: School of Pharmacy, Uimyung Research Instititue for Neuroscience/Sahmyook University, Seoul, Korea, Republic Of
    Chrislean Jun Botanas: School of Pharmacy, Uimyung Research Instititue for Neuroscience/Sahmyook University, Seoul, Korea, Republic Of
    Raly James Custodio: School of Pharmacy, Uimyung Research Instititue for Neuroscience/Sahmyook University, Seoul, Korea, Republic Of
    Irene Joy dela Peña: School of Pharmacy, Uimyung Research Instititue for Neuroscience/Sahmyook University, Seoul, Korea, Republic Of
    Mikyoung Kim: School of Pharmacy, Uimyung Research Instititue for Neuroscience/Sahmyook University, Seoul, Korea, Republic Of
    Kyungyi You: School of Pharmacy, Uimyung Research Instititue for Neuroscience/Sahmyook University, Seoul, Korea, Republic Of
    Taeseon Woo: School of Pharmacy, Uimyung Research Instititue for Neuroscience/Sahmyook University, Seoul, Korea, Republic Of
    Hee Jin Kim: School of Pharmacy, Uimyung Research Instititue for Neuroscience/Sahmyook University, Seoul, Korea, Republic Of
    Jae Hoon Cheong: School of Pharmacy, Uimyung Research Instititue for Neuroscience/Sahmyook University, Seoul, Korea, Republic Of
  • Abstract:

    Methods

    "EN-US">We exposed adolescent Sprague–Dawley rats to cigarette smoke or nicotine, for 14 days, and then the addictive effects of nicotine were evaluated during adulthood, through the conditioned place preference (CPP) and self-administration (SA) tests. In addition, we assessed the expression of α4-containing "EN-US">nicotinic"EN-US">..

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