Inhibition of nlrp3 inflammasome by curcumin in macrophages

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: LEE, Hye Eun (The catholic university of Korea, college of pharmacy, Bucheon-si, Korea, Republic Of)
  • Co-author(s): Hye Eun Lee:
    Joo Hyeon Jang: college of pharmacy, The catholic university of Korea, Bucheon-si, Korea, Republic Of
    Joo Young Lee: college of pharmacy, The catholic university of Korea, Bucheon-si, Korea, Republic Of
  • Abstract:

    Methods

    The bone marrow-derived primary macrophages (BMDMs) were primed with lipopolysaccharide (LPS). To exclude the possibility that curcumin might affect LPS-mediated signaling pathways, curcumin was added after washing out the LPS. The cells were treated with curcumin for 1 hr and were stimulated with ATP or nigericin. To determine the..

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