Inhibition of nlrp3 inflammasome by curcumin in macrophages

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: LEE, Hye Eun (The catholic university of Korea, college of pharmacy, Bucheon-si, Korea, Republic Of)
  • Co-author(s): Hye Eun Lee:
    Joo Hyeon Jang: college of pharmacy, The catholic university of Korea, Bucheon-si, Korea, Republic Of
    Joo Young Lee: college of pharmacy, The catholic university of Korea, Bucheon-si, Korea, Republic Of
  • Abstract:

    Background

    Inflammasomes are composed of NOD-like receptor families, and an adaptor protein ASC, and pro-caspase-1, responding to pathogens as well as danger signals derived from host or environment. The activation of inflammasomes culminates in the maturation of IL-1β and IL-18, contributing to the regulation of immune responses. Curcumin..

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