In situ forming implant formulations as multi-purpose prevention technologies

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: HAECK, Clement (Queen's University Belfast, School of Pharmacy, Belfast, United Kingdom)
  • Co-author(s): Clement M. Haeck: School of Pharmacy, Queen's University Belfast, Belfast, United Kingdom
    Thakur Raghu Raj Singh: School of Pharmacy, Queen's University Belfast, Belfast, United Kingdom
    R. Karl Malcolm: School of Pharmacy, Queen's University Belfast, Belfast, United Kingdom
  • Abstract:

    Methods

    ISFI formulations were prepared by dissolving PLGA in N-methyl-2-pyrrolidone (10—30% w/w). Work of syringeability (WoS) and maximum force (MF) of expulsion were investigated using needles of different diameter. A texture analyser was used to expel the formulations from a 1 mL syringe at different rates.

    Results

    A decrease in the needle..

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