Determination of inh and rifampicin in dbs sample of tuberculosis patients to support therapeutic drug monitoring

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: HARAHAP, Yahdiana (Universitas Indonesia, Faculty of Pharmacy, Depok, Indonesia)
  • Co-author(s): Yahdiana Harahap:
    Ghina Ashiila: Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
    Fauzan Alkindy: Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
    Rahmayanti Rahmayanti: Bekasi Public Hospital, Bekasi, Indonesia
  • Abstract:

    Methods

    40µl of whole blood was collected from patients finger at 2 and 6 hours after oral administration of the fixed dose combination (FDC) tablet containing RIF and INH. Then it was plotted on the DBS CAMAG paper and dried for 3 hours. Afterward the whole plot was punched and extracted with methanol containing cilostazol as internal standard.

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