Preparation and evaluation of parenteral formulation of docetaxel using micelle delivery system

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: KIM, Junhee (Korea, Republic Of)
  • Co-author(s): Junhee Kim:
    Yeji Seo: College of pharmacy, Yonsei university, Incheon, Korea, Republic Of
    Sung-Joo Hwang: College of pharmacy, Yonsei university, Incheon, Korea, Republic Of
  • Abstract:

    Background

    Docetaxel is widely used anti-cancer agent, but the clinical usefulness of this drug is limited by its poor solubility. Some water-miscible cosolvents are used to improve drug insolubility. However these co-solvents easily cause precipitations. 

    Purpose

    In this study, we developed an aqueous-based i.v. formulation of docetaxel that doesn’t ..

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