Effect on pvp / tadalafil solid dispersion prepared using supercritical anti-solvent method with operating parameters

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: HAM, Gun Joo (Korea, Republic Of)
  • Co-author(s): Gun Joo Ham: College of pharmacy, Yonsei university, Incheon, Korea, Republic Of
    In Taek Shin: College of pharmacy, Yonsei university, Incheon, Korea, Republic Of
    Sung-Joo Hwang: College of pharmacy, Yonsei university, Incheon, Korea, Republic Of
  • Abstract:

    Background

    Various parameters effect Supercritical anti-solvent (SAS) process, which was utilized to produce tadalafil solid dispersion submicron particles.

    Purpose

    The purpose of this study is determining patterns of SAS processing parameters (temperature, pressure, and drug concentration) that could improve dissolution rate.

    Methods

    The SAS process..

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