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Preparation of siRNA-spiked gold nanoparticles and evaluation of their physicoshemical properties amd anti-angiogenic effects in vitro

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: OZEKI, Tetsuya (Nagoya City University, Drug Delivery and Nano Pharmaceutics, Nagoya, Japan)
  • Co-author(s): Tetsuya Ozeki: Drug Delivery and Nano Pharmaceutics, Nagoya City University, Nagoya, Japan
    Takao Takeuchi: Drug Delivery and Nano Pharmaceutics, Nagoya City University, Nagoya, Japan
    Tatsuaki Tagami: Drug Delivery and Nano Pharmaceutics, Nagoya City University, Nagoya, Japan
  • Abstract:

    Backgrounds

    Angiogenesis causes various diseases such as age-related macular degeneration. We focused on siRNA as a novel type of anti-angiogenic drug. siRNA conducts sequence-specific gene silencing and has anti-angiogenic effect via Toll like receptor 3 signaling pathway.

    Aims

    In this study, we tried to establish the one-step preparing method of

    ..

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Last update 4 October 2019

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