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Cost-effective delivery of hydrophobic drugs by surfactant solubilization: fundamental insights for practical applications

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: VINAROV, Zahari (Sofia University, Chemical and Pharmaceutical Engineering, Sofia, Bulgaria)
  • Co-author(s): Zahari Vinarov: Chemical and Pharmaceutical Engineering, Sofia University, Sofia, Bulgaria
    Slavka Tcholakova: Chemical and Pharmaceutical Engineering, Sofia University, Sofia, Bulgaria
    Nikolai Denkov: Chemical and Pharmaceutical Engineering, Sofia University, Sofia, Bulgaria
  • Abstract:

    Backgrounds

    More than 50 % of NCE have poor water solubility, limiting clinical application. One route to increase drug solubility is by surfactant solubilization. However, the lack of clear fundamental basis for appropriate surfactant selection hinders broader use of this simple and cost-effective technology. 

    Aims

    To reveal the rules for surfactant

    ..

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Last update 4 October 2019

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