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High Throughput Solubility Screening Method for Assessing Feasibility of Developing Self-Emulsifying Lipid Based Formulations
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Poster
- By: BERNAERTS, Ad (Patheon Softgels B.V., Pharmaceutical Development Services, Tilburg, Netherlands)
- Co-author(s): Ad bernaerts: Pharmaceutical Development Services, Patheon Softgels B.V., Tilburg, Netherlands
Martin Piest: Pharmaceutical Development Services, Patheon Softgels B.V., Tilburg, Netherlands
BackgroundsFor development of a feasible lipid based formulation in soft gelatin capsules a good solubility of the therapeutic ingredient in the lipid vehicle is required to ultimately minimize capsule size. For developing a self-emulsifying system, the excipients need to be selected based upon drug compound solubility and chemical compatibility.
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Last update 4 October 2019