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High Throughput Solubility Screening Method for Assessing Feasibility of Developing Self-Emulsifying Lipid Based Formulations

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: BERNAERTS, Ad (Patheon Softgels B.V., Pharmaceutical Development Services, Tilburg, Netherlands)
  • Co-author(s): Ad bernaerts: Pharmaceutical Development Services, Patheon Softgels B.V., Tilburg, Netherlands
    Martin Piest: Pharmaceutical Development Services, Patheon Softgels B.V., Tilburg, Netherlands
  • Abstract:

    Backgrounds

    For development of a feasible lipid based formulation in soft gelatin capsules a good solubility of the therapeutic ingredient in the lipid vehicle is required to ultimately minimize capsule size. For developing a self-emulsifying system, the excipients need to be selected based upon drug compound solubility and chemical compatibility.

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Last update 4 October 2019

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