Ubiquitin-proteasome system as a cellular defense mechanism against methylmercury-induced cytotoxicity
- At: 2004 FIP Congress in New Orleans (USA)
- Type: Poster
- By: HWANG, Gi-Wook (Tohoku University, Graduate School of Pharm. Sci., Sendai, Japan)
- Co-author(s): Furuchi (Tohoku University, SENDAI, Japan)
Naganuma (Tohoku University, SENDAI, Japan)
We have recently identified CDC34 (also referred to as UBC3) as a methylmercury resistance gene. CDC34 encodes one of the ubiquitin-conjugating enzymes that catalyze ubiquitin transfer onto substrate proteins, a important step for protein degradation via ubiquitin-proteasome pathway. To elucidate the mechanism how Cdc34 reduce the yeast.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.