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Prenatal and postnatal ritodrine pharmacokinetics of women and twin neonates

  • At: 2014 FIP Congress in Bangkok (Thailand)
  • Type: Poster
  • By: INOTSUME, Nobuo (Hokkaido Pharmaceutical University, Clinical Pharmacology, Otaru, Japan)
  • Co-author(s): Soma, Mayuko (Tenshi Hospital, Otaru, Japan)
    Konda, Ainari (Hokkaido Pharmaceutical University, Otaru, Japan)
    Toda, Takaki (Hokkaido Pharmaceutical University, Otaru, Japan)
    Mukai, Yuji (Hokkaido Pharmaceutical University, Otaru, Japan)
    Kishimoto, Shuichi (Kobegakuin University, Kobe, Japan)
    Fukushima, Shoji (Kobegakuin University, Kobe, Japan)
    Fujieda, Satoko (Tenshi Hospital, Otaru, Japan)
    Yoshida, Hiroshi (Tenshi Hospital, Otaru, Japan)
  • Abstract:

    Pregnant women in Japan requiring hospitalization for threatened labor often receive continuous infusions of ritodrine, a β2-selective agonist. Ritodrine can cross the placenta and its pharmacological effects in neonates can include tachycardia, hypoglycemia, and intestinal paralysis, which are matters of major concern.

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Last update 4 October 2019

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