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Single-point sampling for assessment of oral metformin exposure and bioequivalence

  • At: 2014 FIP Congress in Bangkok (Thailand)
  • Type: Poster
  • By: CHENG, Ching-Ling (China Nan University of Pharmacy and Science, Department of Pharmacy, Tainan city, China Taiwan)
  • Co-author(s): Chiu, Chiung-Yi (Nat'l Cheng Kung Univ., Instit of Clinical Pharmacy and Pharmaceutical Sciences, Tainan city, China Taiwan)
    Chou, Chen-Hsi (Nat'l Cheng Kung Univ., Instit of Clinical Pharmacy and Pharmaceutical Sciences, Tainan city, China Taiwan)
  • Abstract:

    Background: The area under the concentration time curve (AUC) and peak plasma concentration (Cmax) are the exposure parameters used for bioequivalence (BE) assessment. The estimation of AUC and Cmax requires serial blood sampling and quantification which is time-consuming and expensive.
    Aims: This study evaluated the feasibility of using a single..

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Last update 4 October 2019

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