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Toxicological examination of three photoinitiators found in intravenous injection solution

  • At: 2014 FIP Congress in Bangkok (Thailand)
  • Type: Poster
  • By: KAWASAKI, Yoichi (Okayama University Hospital, Department of Pharmacy, Okayama, Japan)
  • Co-author(s): Tsuboi, Chiaki (Department of Clinical Pharmacy, Okayama University Graduate School of Medical,, Okayama, Japan)
    Kuhara, Noriko (Department of Clinical Pharmacy, Okayama University Graduate School of Medical,, Okayama, Japan)
    Morizane, Miwa (Department of Clinical Pharmacy, Okayama University Graduate School of Medical,, Okayama, Japan)
    Takai, Mariko (Department of Clinical Pharmacy, Okayama University Graduate School of Medical,, Okayama, Japan)
    Yagi, Kenta (Department of Clinical Pharmacy, Okayama University Graduate School of Medical,, Okayama, Japan)
    Esumi, Satoru (Okayama University Hospital, Okayama, Japan)
    Kitamura, Yoshihisa (Okayama University Hospital, Okayama, Japan)
    Sendo, Toshiaki (Okayama University Hospital, Okayama, Japan)
  • Abstract:

    â… .Background
    Our previous studies revealed the presence of the photoinitiators 1-hydroxycyclohexyl phenyl ketone (1-HCHPK), methyl-2-benzoylbenzoate (MBB), and 2-methyl-4'-(methylthio)-2-morpholinopropiophenone (MTMP) in intravenous (i.v.) injection solution. In previous in vitro studies, it was reported that photoinitiators were cytotoxic...

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Last update 4 October 2019

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