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Anticoagulant activity of coumarin from kluwak (pangium edule reinw.) seeds based on prothrombin time in rat

  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Presentation
  • By: SUMARDI, Dara Prabandari (Sanata Dharma University, Pharmacy, Yogyakarta, Indonesia)
  • Co-author(s): Dwiatmaka, Yohanes (Sanata Dharma University, Yogyakarta, Indonesia)
    Dwiatmaka, Yohanes (Sanata Dharma University, Yogyakarta, Indonesia)
  • Abstract:

    Warfarin has been widely used in pharmaceutical applications as anticoagulant for decades. Seed of kluwak (Pangium edule Reinw.) is a natural source of coumarin. Previous research found that ethanol extract of kluwak seeds containing coumarin at 91,887%. Since warfarin is one of coumarin derivatives, the pharmacological activity of coumarin..

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Last update 4 October 2019

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