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The involvement of fatty acid-binding protein 5 in the blood-brain barrier transport of docosahexaenoic acid

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Presentation
  • By: PAN, Yijun (MONASH UNIVERSITY, PHARMACEUTICS, Parkville, Australia)
  • Co-author(s): Porter, Christopher (MONASH UNIVERSITY, Parkville, Australia)
    Scanlon, Martin (MONASH UNIVERSITY, Parkville, Australia)
    Nicolazzo, Joseph (MONASH UNIVERSITY, Parkville, Australia)
  • Abstract:

    Background Docosahexaenoic acid (DHA) is an essential fatty acid required for brain function. The brain has limited ability to synthesise DHA and therefore plasma-derived DHA must be transported across the blood-brain barrier (BBB). Given the low aqueous solubility of DHA, an intracellular carrier protein may be essential to shuttle DHA across the ..

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Last update 4 October 2019

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