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Optimising the impact of uptake and efflux transporters in cancer chemotherapy

  • In: 8D1 - Exploiting scientific knowledge of biological transporters for practical therapeutic benefit on Thursday, 4 October 2012, 09:00-12:00
  • At: Amsterdam (the Netherlands) (2012)
  • Type: Presentation
  • By: SCHELLENS, Jan (The Netherlands Cancer Institute, Clinical Pharmacology, Amsterdam, Netherlands)
  • Co-author(s): Beijnen, J.H. (Slotervaart Hospital, Amsterdam, Netherlands)
    Huitema, A.D.R. (Slotervaart Hospital, Amsterdam, Netherlands)
    Nuijen, B. (Slotervaart Hospital, Amsterdam, Netherlands)
  • Abstract:

    Oral administration of anticancer drugs is most often preferred over intravenous administration, as it is convenient for patients, prevents hospitalization and reduces costs of the therapy. However, the use of oral administration is often hampered by low oral bioavailability for instance of the taxanes, paclitaxel and docetaxel. Limited oral


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Last update 28 September 2023

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