Anticonvulsant and sedative-hypnotic activity of novel 6,7,8,9 tetra hydro-5h-5-phenyl-2-benzylidine-3-substituted hydrazino thiazolo (2, 3-b) quinazoline derivatives and analogues

• In: Medicinal Chemistry Posters
• At: Hyderabad (India) (2011)
• Type: Poster
• Poster code: MC-P-02
• By: PANNEERSELVAM, Theivendren (Srinivas College of Pharmacy, Mangalore, India)
• Co-author(s): Vijayarajkumar, Palanirajan (UCSI (University College Sadaya International) University, Kuala Lumpur, Malaysia)
  Shabaraya, Ramakrishna (Srinivas College of Pharmacy, Mangalore, India)
  
• Abstract:

  Introduction- A few novel 6,7,8,9 Tetra hydro-5H-5-phenyl-2-benzylidine-3-substituted hydrazino thiazolo (2, 3-b) quinazoline were synthesized and evaluated for anticonvulsant, neurotoxicity, sedative-hypnotic and phenobarbitone-induced hypnosis potentiation test. Method- After i.p. injection to mice at doses of 30, 100, and 300 mg/kg body weight

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