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Study of fast release cefpodoxime proxetil tablet using complexation and solid dispersion techniques

  • In: Industrial Pharmacy Posters
  • At: Hyderabad (India) (2011)
  • Type: Poster
  • Poster code: IPS-P-01
  • By: BUDHATHOKI, Uttam (Department of Pharmacy, Kathmandu University, Dhulikhel, Nepal)
  • Co-author(s): Aryal, Bishnu Prasad (Department of Pharmacy, Kathmandu University, Dhulikhel, Nepal)
    Thapa, Panna (Department of Pharmacy, Kathmandu University, Dhulikhel, Nepal)
  • Abstract:

    Background information: Bioavailability of cefpodoxime proxetil (CP) is 50% due to solubility, gelation and luminal metabolism. Complexation in stoichiometric ratio of 1:1 for β-cyclodextrins (β-CD) and CP was more sensitive to microbes than uncomplexed one and solid dispersion in polyvinylpyrrolidone K-30 improved its bioavailability. In

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Last update 28 September 2023

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