Trace determination of donepezil by capillary electrophoresis with liquid-liquid extraction and head-column field-amplified sample stacking in patients’ plasma with alzheimer’s disease

• In: SIG Bioavailability/Bioequivalence - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: BB-P-050
• By: CHEN, Su-Hwei (Kaohsiunh Medical University, Kaohsiung, China Taiwan)
• Abstract:

  A sensitive high-performance capillary electrophoresis (CE) with head-column field-amplified sample stacking (FASS) in binary system has been developed for the determination of donepezil, a centrally acting acetylcholine esterase inhibitor, in human plasma. Donepezil was extracted from plasma with isopropanol-hexane (3:97 v/v). The organic phase

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