Simultaneous determination of ciprofloxacin hydrochloride and metronidazole in spiked human plasma by ultra performance liquid chromatography-tandem mass spectroscopy

• In: Posters: Analytical Sciences and Pharmaceutical Quality
• At: Bangkok (Thailand) (2014)
• Type: Poster
• Poster code: POS-ASP003
• By: MANDOUR, Asmaa (Cairo, Egypt)
• Co-author(s): El-Bagary, Ramzia (Cairo University, Giza, Egypt)
  El-Zaher, Asmaa (Cairo University, Giza, Egypt)
  Elkady, Ehab (Cairo University, Giza, Egypt)
  
• Abstract:

  Ciprofloxacin HCl (CIP) and Metronidazole (MET) are antibacterial drugs used in combination for treatment of mixed aerobic/anaerobic infections. An UPLC-MS/MS method was developed for the simultaneous estimation of CIP and MET in spiked human plasma using sildenafil citrate as an internal standard (IS). Protein precipitation was used for analyte..

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