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A computational approach of structure-based virtual screening towards the discovery of selective 5α-reductase type ii inhibitors for BPH treatment

  • At: Seville (Spain) (2022)
  • Type: Poster
  • Poster code: NMS-027
  • By: REFAAT, Hanan (Future University In Egypt, Egypt)
  • Co-author(s): Prof Hanan Refaat (Future University In Egypt, Cairo, Egypt)
    Prof Nasser S.M. Ismail, Pharmaceutical Chemistry
    Lecturer Asmaa A. Mandour, Pharmaceutical Chemistry
  • Abstract:

    5α-Reductase type II (5αR2) inhibition has been considered one of the most promising strategies for Benign Prostatic Hyperplasia (BPH) treatment. This enzyme catalyses androgen dihydrotestosterone (DHT) formation from testosterone leading to elevated levels of DHT responsible for the abnormal growth of prostate in male humans. In this research,..

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Last update 28 September 2023

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