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Application of fenofibrate solid dispersion for bioavailability enhancement by hot-melt extrusion

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: LIU, Amy (Industrial Technology Research Institute, 1. Pharmaceutical Optimization Technology Division, Biomedical Technology and De, Hsinchu, China Taiwan)
  • Abstract:

    Low aqueous solubility for BCS II drugs resulted in poor oral bioavailability has been recognized as an increasingly challenge in the pharmaceutical industry. Hot-melt extrusion is one of the scale-up processes of the solid dispersion preparation in the pharmaceutical industry. The objective of this study was to improve the dissolution rate and..

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Last update 4 October 2019

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