Application of fenofibrate solid dispersion for bioavailability enhancement by hot-melt extrusion

• In: Posters D - Formulation Design and Pharmaceutical Technology
• At: PSWC, Melbourne (Australia) (2014)
• Type: Poster
• Poster code: PD-080
• By: LIU, Amy (Industrial Technology Research Institute, 1. Pharmaceutical Optimization Technology Division, Biomedical Technology and De, Hsinchu, China Taiwan)
• Abstract:

  Low aqueous solubility for BCS II drugs resulted in poor oral bioavailability has been recognized as an increasingly challenge in the pharmaceutical industry. Hot-melt extrusion is one of the scale-up processes of the solid dispersion preparation in the pharmaceutical industry. The objective of this study was to improve the dissolution rate and..

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