Buccal silymarin liposomal delivery system: preparation and investigation applying factorial design

• In: SIG Bioavailability / Bioequivalence - Poster Session
• At: Cairo (Egypt) (2005)
• Type: Poster
• Poster code: BB-P-017
• By: MAHMOUD (Faculty of Pharmacy, Cairo University, Cairo, Egypt)
• Co-author(s): El-Samaligy (Faculty of pharmacy, Cairo University, CAIRO, Egypt)
  Afifi (Faculty of pharmacy, Cairo University, CAIRO, Egypt)
  
• Abstract:

  Silymarin, a natural lipotropic agent of low bioavailability from oral products, is prepared in a buccal liposomal delivery system. Silymarin liposomes were prepared using lecithin/cholesterol mixtures. Additives were explored in a full 2(3) factorial experimental design regarding drug entrapment efficiency. Additives used to optimize liposomal..

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