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Low dose drug and lubricant quantification in powder blends by near infrared spectroscopy

  • At: 2011 FIP Congress in Hyderabad (India)
  • Type: Presentations + Posters
  • By: MARTINEZ, Lizbeth (University of Basel, Basel, Switzerland)
  • Co-author(s): Liesum, Lorenz (Novartis Pharma AG, Basel, Switzerland)
    Betz, Gabriele (University of Basel, Basel, Switzerland)
  • Abstract:

    Blending is a fundamental but critical process in the manufacture of solid dosage forms, especially for the formulations containing low dose drugs. Near infrared (NIR) spectroscopy has shown a great potential in real-time monitoring of powder blending processes.
    The aim of this study was to predict the low load components (drug and lubricant) in a

    ..

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Last update 4 October 2019

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