Rapid determination of clobazam and desmethylclobazam in human plasma by HPLC
- At: 2005 FIP Congress in Cairo (Egypt)
- Type: Poster
- By: ROUINI, Mohammadreza (Tehran U of Medical Sciences, Pharmaceutics, Tehran, Iran)
- Co-author(s): Hosseinzadeh Ardakani (Tehran U of Medical Sciences, Tehran, Iran)
Mokhberi (Tehran U of Medical Sciences, Tehran, Iran)
Badri (Tehran U of Medical Sciences, Tehran, Iran)
Aim: The study was designed to develop a rapid HPLC method using Chromolith TM column for sensitive determination of clobazam (CLB) and its main metabolite N-desmethylclobazam (NDCLB/IS) in human plasma with an acceptable LOQ for pharmacokinetic studies. Methods: The chromatographic apparatus consisted of a low-pressure gradient HPLC pump, a UV.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.