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Phenanthrenes from dendeobium nobile stem attenuated hepatic stellate cell proliferation

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: KIM, Young Choong (College of Pharmacy, Seoul National University, Seoul, South-Korea)
  • Co-author(s): Yang, Hyekyung (College of Pharmacy, Seoul National University, SEOUL, South-Korea)
    Sung, Sang Hyun (College of Pharmacy, Seoul National University, SEOUL, South-Korea)
    Chung, Kyu Hyuck (College of Pharmacy, Sungkyunkwan University, SUWON, South-Korea)
    Lee, Beom Jin (College of Pharmacy, Kangwon National University, CHUNCHEON, South-Korea)
    Kim, Jinwoong (College of Pharmacy, Seoul National University, SEOUL, South-Korea)
  • Abstract:

    Hepatic stellate cells (HSCs) are considered to play a key role in pathogenesis of liver fibrosis. Employing HSC-T6, a rat hepatic stellate cell line as an in vitro assay system, it was found that the methanolic extract of Dendrobium nobile stem showed significant inhibition on of HSC-T6 cell proliferation. Bioactivity-guided fractionation led to

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Last update 4 October 2019

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