Phenanthrenes from dendeobium nobile stem attenuated hepatic stellate cell proliferation

• In: Natural Products Posters
• At: Lisbon (Portugal) (2010)
• Type: Poster
• Poster code: NP-P-022
• By: KIM, Young Choong (College of Pharmacy, Seoul National University, Seoul, South-Korea)
• Co-author(s): Yang, Hyekyung (College of Pharmacy, Seoul National University, SEOUL, South-Korea)
  Sung, Sang Hyun (College of Pharmacy, Seoul National University, SEOUL, South-Korea)
  Chung, Kyu Hyuck (College of Pharmacy, Sungkyunkwan University, SUWON, South-Korea)
  Lee, Beom Jin (College of Pharmacy, Kangwon National University, CHUNCHEON, South-Korea)
  Kim, Jinwoong (College of Pharmacy, Seoul National University, SEOUL, South-Korea)
  
• Abstract:

  Hepatic stellate cells (HSCs) are considered to play a key role in pathogenesis of liver fibrosis. Employing HSC-T6, a rat hepatic stellate cell line as an in vitro assay system, it was found that the methanolic extract of Dendrobium nobile stem showed significant inhibition on of HSC-T6 cell proliferation. Bioactivity-guided fractionation led to

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