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Development and optimization of multiple-unit controlled release dosage form of a highly water soluble for once-daily administration

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: BASALIOUS, Emad (Faculty of pharmacy, Cairo university, Cairo, Egypt)
  • Co-author(s): Shoukri, Raguia (Faculty of pharmacy, Cairo university, CAIRO, Egypt)
    Shamma, Rehab (Faculty of pharmacy, Cairo university, CAIRO, Egypt)
  • Abstract:

    A controlled release multiple-unit preparation of betahistine diHCl (BHCL), a short half-life freely water soluble drug, was developed to allow once-daily administration to improve patient compliance. BHCL was complexed with cation exchange resins having different particle size and degree of cross linking. BHCL-resin complex that provided the..

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Last update 4 October 2019

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