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Optimization of a modified quasi-emulsion solvent diffusion method for the preparation of directly compressible ibuprofen spheres

  • At: 2009 FIP Congress in Istanbul (Turkey)
  • Type: Poster
  • By: ELFAHAM, Tahani Hassan (Faculty of Faculty - Assiut university, Assiut, Egypt)
  • Co-author(s): Ibrahim1, Said (Faculty of Faculty - Assiut university, Assiut, Egypt)
    Helmy, Abdel Rahman (Departement of research and development, CID Co, Assiut Factory, Assiut, Assiut, Egypt)
  • Abstract:

    In a previous study(1), a modified QESD technique was applied successfully to improve the poor flowability, compressibility and dissolution properties of ibuprofen (class II drug). Different polymers (PVP, HPMC, PEG 4000) and/or surfactants (Tween 80 and Myrj 53)were used to obtain spheres of optimum size (300-600 µm) and improved dissolution

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Last update 4 October 2019

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