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Combination of hydrophilic polymer to solubilize and formulation chrysosplenol C in solid dispersion

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: PARK, Jeong-Sook (Chungnam National University, College of Pharmacy, Daejeon, Korea, Republic Of)
  • Co-author(s): Choon Lian Ng: College of Pharmacy, Chungnam National University, Daejeon, Korea, Republic Of
    Chang-Seon Myung: College of Pharmacy, Chungnam National University, Daejeon, Korea, Republic Of
    Jeong-Sook Park: College of Pharmacy, Chungnam National University, Daejeon, Korea, Republic Of
  • Abstract:

    Backgrounds

    Chrysosplenol C (CRSP), a flavone found in several medicinal plants, is specific inhibitors of poliovirus and rhinovirus. Moreover, CRSP shows cytotoxic activity against cancer cell lines and positive inotropic action on cardiac myocytes. However, CRSP is poorly soluble in water. 

    Aims

    To overcome problems associated with the solubility,

    ..

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Last update 4 October 2019

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