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Absorption enhancing mechanisms of gemini surfactants on the intestinal absorption of poorly absorbable drugs in rats

  • In: Posters G - Pharmacokinetics (PK), Pharmacodynamics (PD) and Systems Pharmacology
  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Poster
  • Poster code: PG-021
  • By: ALAMA, Tammam (Kyoto Pharmaceutical University, Biopharmaceutics, Kyoto, Japan)
  • Co-author(s): Kusamori, Kosuke (Kyoto Pharmaceutical University, Kyoto, Japan)
    Katsumi, Hidemasa (Kyoto Pharmaceutical University, Kyoto, Japan)
    Sakane, Toshiyasu (Kyoto Pharmaceutical University, Kyoto, Japan)
    Yamamoto, Akira (Kyoto Pharmaceutical University, Kyoto, Japan)
  • Abstract:

    More than 60% of marketed formulations are oral formulations. Unfortunately, the intestinal absorption of hydrophilic macromolecules, peptide and protein drugs after their oral administration is very poor. Absorption enhancers are considered to be one of the most promising methods to enhance the intestinal absorption. In this research, we focused..

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Last update 4 October 2019

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