Selection of polymeric precipitation inhibitors for use with poorly water soluble drugs
- In: Posters D - Formulation Design and Pharmaceutical Technology
- At: PSWC, Melbourne (Australia) (2014)
- Type: Poster
- Poster code: PD-025
- By: WARREN, Dallas (Monash Institute of Pharmaceutical Science, Drug Delivery, Disposition and Dynamics, Parkville, Australia)
- Co-author(s): Bergstr, Christel A.S. (Uppsala University Drug Optimization and Pharmaceutical Profiling Platform, Uppsala, Sweden)
Benameur, Hassan (Capsugel R&D, Strasbourg, France)
Williams, Hywel (Capsugel R&D, Strasbourg, France)
Porter, Christopher (Monash Institute of Pharmaceutical Science, Parkville, Australia)
Pouton, Colin (Monash Institute of Pharmaceutical Science, Parkville, Australia)
The presence of polymers within solid dose dispersions and lipid based formulations, can promote the maintenance of drug supersaturation after dissolution or dispersion/digestion of the vehicle in the gastrointestinal tract.
To provide a deeper understanding of the molecular determinants of polymer precipitation inhibition the precipitation.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.