A validated method high-performance liquid chromatography tandem mass spectrometry (hplc-ms-ms) for determination of isoniazid and acetylisoniazid in plasma human to determine acetylator phenotype
- At: 2006 FIP Congress in Salvadore (Brazil)
- Type: Poster
- By: GONCALVES, J.C. (Fac Farmácia-UFRJ, Rio De Janeiro, Brazil)
- Co-author(s): Neves de Miranda, Claudia (Fac Farmácia-UFRJ, RIO DE JANEIRO, Brazil)
To establish a useful method for acetylator phenotypication and therapeutic drug monitoring of patients receiving isoniazid a rapid and sensitive method using high-performance liquid chromatography tandem mass spectrometry (HPLC-MS-MS) was developed and evaluated for simultaneous quantitative determination of isoniazid and its major metabolite,.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.