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Analysis of O6 - alkylguanine in breast cancer patients’ blood during recurrent oral administration of cyclophosphamide

  • At: Istanbul (Turkey) (2009)
  • Type: Poster
  • By: HARAHAP, Yahdiana (Department of Pharmacy, FMIPA, University of Indonesia, Depok, Indonesia)
  • Co-author(s): Andalusia, Rizka (Dharmais Cancer Hospital, Jakarta, Indonesia)
  • Abstract:

    Cyclophosphamide as one of the alkylating agents has been widely used in the cancer chemotherapy because it is highly effective in eradicating the cancer cells by directly reacting with DNA so that DNA is mutated by the alkylating process and lost its function of cell replication. The mechanism of alkylating agent's reaction with DNA is simple and


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Last update 4 October 2019

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