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STATISTICAL OPTIMIZATION OF FLUCONAZOLE NANOVESICLES FOR TREATMENT OF FUNGAL RHINOSINUSITIS

  • At: 2019 FIP Congress in AbuDhabi (United Arab Emirates)
  • Type: Poster
  • By: HASSAN, Nourhan (Gulf medical university, college of pharmacy, United Arab Emirates)
  • Co-author(s): Nourhan khaled Hassan: College of Pharmacy, Gulf Medical University, Ajman, United Arab Emirates
    Hisham Mohamed: College of Pharmacy, Gulf Medical University, Ajman, United Arab Emirates
    Mohamed Haider: Department of pharmaceutics and Pharmaceutical Technology, College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt
    Ahmed Luay: Medical Laboratory Sciences, College of Health Sciences, Gulf Medical University, Ajman, United Arab Emirates
    Ibrahim Elsayed: College of Pharmacy, Gulf Medical University, Ajman, United Arab Emirates;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt
  • Abstract:

    Background

    Topical application of fluconazole was found to be promising for the postsurgical treatment of fungal rhinosinusitis. Fluconazole has poor aqueous solubility which may affect its efficacy after nasal administration.

    Methods

    Cetyl alcohol, Tween and chitosan were utilized in different ratios to prepare the nanovesicles using a modified thin

    ..

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Last update 4 October 2019

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