Development of a model-based dose-individualisation approach with an application to routine clinical data

• In: One size doesn't fit all: Dose individualisation with population pharmacology on Tuesday, 12 September 2017, 09:00-12:00
• At: Seoul (South Korea) (2017)
• Type: Presentation
• By: GUK, Jinju (Yonsei University College of Medicine, Seoul, Korea, Republic Of)
• Co-author(s): Jinju Guk
  Dongwoo Chae
  Kyungsoo Park
  
• Abstract:

  With the development of new effective antiepileptic agents, the use of phenytoin has kept decreasing. Large inter-individual variability and narrow therapeutic range in drug concentration is another reason for decrease in phenytoin use. However, phenytoin is still an essential agent for second-line treatment of status epilepticus when patients do

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