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Bioequivalence of cefditoren in human and pharmacokinetics of absorption in rats

  • At: Beijing (China) (2007)
  • Type: Poster
  • By: LIU, Kexin (Dalian Medical University, Dalian, China)
  • Co-author(s): Liu, qi (Dalian Medical University, DALIAN, China)
    Yao, jihong (Dalian Medical University, DALIAN, China)
    Zhang, qinghao (Dalian Medical University, DALIAN, China)
  • Abstract:

    Objective:We investigated bioequivalence of cefditoren (CDTR) between cefditoren pivoxil (CDTR-PI) tablet (R) and CDTR-PI granule (T) in 24 healthy male volunteers with a randomized cross over design and examined the biotransformation of CDTR-PI to CDTR in rat intestine. As CDTR is similar to Cephalexin in chemical structure, a challenge is..

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Last update 4 October 2019

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