The xanthine derivative kmup-1 stimulates osteoblastogenesis through activating the bmp/runx-2 signaling pathway
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: LIOU, Shu-Fen (Chia-Nan University of Pharmacy and Science, Department of Pharmacy, Tainan, China Taiwan)
- Co-author(s): Chen, Chiu-Lan (Chia-Nan University of Pharmacy and Science, Tainan, China Taiwan)
Shih, Mei-Fen (Chia-Nan University of Pharmacy and Science, Tainan, China Taiwan)
Background: KMUP-1 is a xanthine derivative with inhibitory activities on the phosphodiesterase (PDE) 3,4 and 5 isoenzymes to suppress the degradation of cyclic AMP and cyclic GMP. However, whether KMUP-1 has any effect on osteoblast differentiation is still unclear.
Aims:This study aimed to investigate the effect of KMUP-1 on differentiation of.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.