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The xanthine derivative kmup-1 stimulates osteoblastogenesis through activating the bmp/runx-2 signaling pathway

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: LIOU, Shu-Fen (Chia-Nan University of Pharmacy and Science, Department of Pharmacy, Tainan, China Taiwan)
  • Co-author(s): Chen, Chiu-Lan (Chia-Nan University of Pharmacy and Science, Tainan, China Taiwan)
    Shih, Mei-Fen (Chia-Nan University of Pharmacy and Science, Tainan, China Taiwan)
  • Abstract:

    Background: KMUP-1 is a xanthine derivative with inhibitory activities on the phosphodiesterase (PDE) 3,4 and 5 isoenzymes to suppress the degradation of cyclic AMP and cyclic GMP. However, whether KMUP-1 has any effect on osteoblast differentiation is still unclear.
    Aims:This study aimed to investigate the effect of KMUP-1 on differentiation of..

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Last update 4 October 2019

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