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Dose-ranging pharmacokinetic and pharmacodynamic assessment of oxytocin after pulmonary administration of a dry powder formulation to postpartum sheep.

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: NGUYEN, Tri-Hung (Monash Institute of Pharmaceutical Sciences, Drug Delivery, Disposition and Dynamics, Parkville, Australia)
  • Co-author(s): Oliver, Victoria L (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
    Patel, Kashyap (Monash University, Parkville, Australia)
    Lambert, Pete (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
    Sou, Tom (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
    Parkington, Helena C (Monash University, Clayton, Australia)
    Prankerd, Richard J (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
    Morton, David A (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
    Kirkpatrick, Carl Mj (Monash University, Parkville, Australia)
    Bischof, Robert J (Monash University, Clayton, Australia)
    Mcintosh, Michelle P (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
  • Abstract:

    Background: The requirement for sterile consumables and trained medical personnel to facilitate administration often limits the utility of the injectable uterotonic, oxytocin, in many low-resource settings. This highlights the need for alternative delivery strategies for this drug.
    Aim: To investigate the pharmacokinetics (PK) of oxytocin after..

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Last update 4 October 2019

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