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Differential binding patterns of lipophilic compounds to fatty acid binding proteins

  • In: Posters G - Pharmacokinetics (PK), Pharmacodynamics (PD) and Systems Pharmacology
  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Poster
  • Poster code: PG-014
  • By: LEE, Gordon (Monash University, Drug Delivery, Disposition and Dynamics, Melbourne, Australia)
  • Co-author(s): Scanlon, Martin (Monash University, Melbourne, Australia)
    Porter, Christopher (Monash University, Melbourne, Australia)
    Nicolazzo, Joseph (Monash University, Melbourne, Australia)
  • Abstract:

    Background: Fatty acid-binding proteins (FABPs) are involved in the intracellular transport of endogenous ligands. However, whether FABPs have the potential to bind to and effect the intracellular trafficking of exogenous lipophilic drugs remains incompletely understood.
    Objective: To assess the differential binding profiles of lipophilic drugs to ..

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Last update 4 October 2019

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