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The impact of different polymers and drug physical state on the dissolution enhancement of solid dispersions

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: GOMES PINA, Maria De F (UCL School of Pharmacy, 29-39 Brunswick Square, London, United Kingdom)
  • Co-author(s): Zhao, Min (UCL School of Pharmacy, London, United Kingdom)
    Pinto, Jo (IMed-UL, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal)
    Sousa, Jo (Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal)
    Craig, Duncan (UCL School of Pharmacy, London, United Kingdom)
  • Abstract:

    BACKGROUND
    The oral bioavailability enhancement of poorly soluble drugs continues to represent a significant issue in drug development. One strategy to overcome this obstacle is the development of solid dispersion formulations using hydrophilic polymers. However, the mechanisms underpinning the dissolution enhancement of these systems are still..

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Last update 4 October 2019

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