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New in vitro tridimensional co-culture intestine cell model for studying the permeability of drugs and nanoparticles

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: SARMENTO, Bruno (University of Porto, INEB-Instituto de Engenharia Biom, Porto, Portugal)
  • Co-author(s): Araujo, Francisca (INEB - University of Porto, Porto, Portugal)
    Pereira, Carla (INEB - University of Porto, Porto, Portugal)
    Leite, Andreia (Instituto Superior de Ci, Gandra, Portugal)
    Ferreira, Domingos (University of Porto, Porto, Portugal)
  • Abstract:

    In vitro cell culture models for studying oral drug absorption during early stages of drug development have become a useful tool in drug discovery and development, with respect to substances throughput and reproducibility.
    In order to design a model that more accurately mimics the intestinal epithelium, we propose an in vitro co-culture based on..

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Last update 4 October 2019

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