New in vitro tridimensional co-culture intestine cell model for studying the permeability of drugs and nanoparticles
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: SARMENTO, Bruno (University of Porto, INEB-Instituto de Engenharia Biom, Porto, Portugal)
- Co-author(s): Araujo, Francisca (INEB - University of Porto, Porto, Portugal)
Pereira, Carla (INEB - University of Porto, Porto, Portugal)
Leite, Andreia (Instituto Superior de Ci, Gandra, Portugal)
Ferreira, Domingos (University of Porto, Porto, Portugal)
In vitro cell culture models for studying oral drug absorption during early stages of drug development have become a useful tool in drug discovery and development, with respect to substances throughput and reproducibility.
In order to design a model that more accurately mimics the intestinal epithelium, we propose an in vitro co-culture based on.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.