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Encapsulation of hydrophilic drug into plga-peg-fol nanoparticles by nanoprecipitation

  • In: Posters D - Formulation Design and Pharmaceutical Technology
  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Poster
  • Poster code: PD-007
  • By: LEE, You Zhuan (Monash University, Jeffrey Cheah School of Medicine and Health Sciences, Selangor, Malaysia)
  • Co-author(s): Ooi, Ing Hong (International Medical University, Kuala lumpur, Malaysia)
    Lee, Chooi Yeng (Monash University, Selangor, Malaysia)
  • Abstract:

    Background and Aims: The main challenge in encapsulating hydrophilic drugs in the nanoparticles (NPs) is the drug's high diffusion rate to the outer aqueous phase during the formulation process, resulting in poor drug loading (DL). The aim of this study was to improve the drug's encapsulation efficiency (EE) and DL by manipulating some of the..

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Last update 4 October 2019

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