Robustness of RP-HPLC method for the determination of valdecoxib and its impurity SC-77852
- At: 2006 FIP Congress in Salvadore (Brazil)
- Type: Poster
- By: ZECEVIC, Mira (Faculty of Pharmacy, Belgrade, Belgrade, Yugoslavia)
- Co-author(s): Savic, Gordana (Medicines and Medical Devices Agency of, BELGRADE, Serbia and Montenegro)
Zivanovic, Ljiljana (Faculty of Pharmacy, Belgrade, BELGRADE, Serbia and Montenegro)
A reversed-phase liquid chromatography method was developed and validated for the evaluation of valdecoxib and impurity SC-77852, which constitutes of a–N-lactosyl sulfonamide and ß–N-lactosyl sulfonamide, i.e. a and ß-anomer. The separation is achieved on monolithic HPLC column. Presented RP-HPLC method is fully validated for its linearity,.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.