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Clinical implications of oxidized ldl in frequent-relapse minimal change nephrotic syndrome patients

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Presentation
  • By: TANAKA, Sachiko (Tokyo University of Pharmacy and Life Sciences, Department of Clinical Pharmacology, Tokyo, Japan)
  • Co-author(s): Kohsaka (Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan)
    Shirai (St. Marianna University School of Medicine, Tokyo, Japan)
    Sudo (Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan)
    Yoshikawa (Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan)
    Nakabayashi (Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan)
    Yoshida (Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan)
    Onda (Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan)
    Sugiyama (Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan)
    Aramaki, Y. (Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan)
    Hirano (Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan)
  • Abstract:

    Background: Nephrotic syndrome is characterized by excessive proteinurea, hypoalbuminemia and hyperlipidemia. One possible explanation for the development of proteinuria is oxidative damage to glomerular cells. Oxidative modifications of LDLs can elicit T cells responses. Minimal change nephrotic syndrome (MCNS) is caused by T cell dysfunction...

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Last update 4 October 2019

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