Nonclassical Antifolates. 5-(2-Aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a New Class of DHFR Inhibitors: Synthesis, Biological Evaluation and Molecular Modeling Study

• In: Posters
• At: Dublin (Ireland) (2013)
• Type: Poster
• By: EL-SUBBAGH, Hussein (Future University, Pharmacy, Cairo, Egypt)
• Co-author(s): Hassan, Ghada (King Saud University, Riyadh, Saudi Arabia)
  El-Messery, Shahenda (Mansoura University, Mansoura, Egypt)
  Al-Omary, Fatmah (King Saud University, Riyadh, Saudi Arabia)
  Al-Rashood, Sarah (King Saud University, Riyadh, Saudi Arabia)
  Shabayek, Marwa (Future University, Cairo, Egypt)
  Abulfadl, Yasmin (Future University, Cairo, Egypt)
  Habib, El-Sayed (Taibah University,, Almadinah Almunawwarah, Saudi Arabia)
  Fayad, Walid (National Research Center,,, Dokki, Giza, Egypt)
  El-Menshawi, Bassem (Future University, Cairo, Egypt)
  
• Abstract:

  
  Nonclassical Antifolates.
  
  5-(2-Aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a New Class of DHFR Inhibitors: Synthesis, Biological Evaluation and Molecular Modeling Study
  
  
  Ghada S. Hassan,^1,2 Shahenda M. El-Messery,³ Fatmah A.M. Al-Omary,¹ Sarah T. Al-Rashood,¹ Marwa I. Shabayek,⁴ Yasmin S. Abulfadl,⁴ El-Sayed E. Habib,⁵ Salwa M.
  
  ..

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