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Nonclassical Antifolates. 5-(2-Aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a New Class of DHFR Inhibitors: Synthesis, Biological Evaluation and Molecular Modeling Study

  • At: 2013 FIP Congress in Dublin (Ireland)
  • Type: Poster
  • By: EL-SUBBAGH, Hussein (Future University, Pharmacy, Cairo, Egypt)
  • Co-author(s): Hassan, Ghada (King Saud University, Riyadh, Saudi Arabia)
    El-Messery, Shahenda (Mansoura University, Mansoura, Egypt)
    Al-Omary, Fatmah (King Saud University, Riyadh, Saudi Arabia)
    Al-Rashood, Sarah (King Saud University, Riyadh, Saudi Arabia)
    Shabayek, Marwa (Future University, Cairo, Egypt)
    Abulfadl, Yasmin (Future University, Cairo, Egypt)
    Habib, El-Sayed (Taibah University,, Almadinah Almunawwarah, Saudi Arabia)
    Fayad, Walid (National Research Center,,, Dokki, Giza, Egypt)
    El-Menshawi, Bassem (Future University, Cairo, Egypt)
  • Abstract:


    Nonclassical Antifolates.


    5-(2-Aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a New Class of DHFR Inhibitors: Synthesis, Biological Evaluation and Molecular Modeling Study



    Ghada S. Hassan,1,2 Shahenda M. El-Messery,3 Fatmah A.M. Al-Omary,1 Sarah T. Al-Rashood,1 Marwa I. Shabayek,4 Yasmin S. Abulfadl,4 El-Sayed E. Habib,5 Salwa M.

    ..

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Last update 4 October 2019

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