Discovery and indentification of new PIN1 inhibitors

• In: Posters
• At: Dublin (Ireland) (2013)
• Type: Poster
• By: ZHANG, Jing (Nstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, The National Laboratory for Screening New Microbial Drugs, Beijing, China)
• Abstract:

  
  Background
  : PIN1 is a member of the evolutionarily conserved peptidyl-prolyl isomerase (PPIase) family of proteins. Following phosphorylation, Pin1 catalyzed prolyl-isomerization induces conformational changes and thereby regulates the function of a number of phosphorylated proteins that play an important role during oncogenesis.
  Aims:
  
  
  ..

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