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Discovery and indentification of new PIN1 inhibitors

  • At: 2013 FIP Congress in Dublin (Ireland)
  • Type: Poster
  • By: ZHANG, Jing (Nstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, The National Laboratory for Screening New Microbial Drugs, Beijing, China)
  • Abstract:


    Background

    : PIN1 is a member of the evolutionarily conserved peptidyl-prolyl isomerase (PPIase) family of proteins. Following phosphorylation, Pin1 catalyzed prolyl-isomerization induces conformational changes and thereby regulates the function of a number of phosphorylated proteins that play an important role during oncogenesis.
    Aims:



    ..

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Last update 4 October 2019

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