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Clinical pharmacology of antibody-based therapeutics

  • At: 2013 FIP Congress in Dublin (Ireland)
  • Type: Presentation
  • By: MAGER, Donald (University at Buffalo, SUNY, Pharmaceutical Sciences, Buffalo, NY, United States of America)
  • Abstract:

    The in vivo disposition (pharmacokinetics, PK) and action (pharmacodynamics, PD) of biological therapeutics tend to be more complex relative to small synthetic compounds, resulting from a combination of pharmacological and physiological factors. Nonlinear dose-dependent effects on drug absorption, disposition, and response are commonplace.

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Last update 4 October 2019

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